Dave Arneson, the co-creator of Dungeons & Dragons, has passed away due to cancer. Dave created the first campaign called Blackmoor and later worked with Gygax to create the original Dungeons and Dragons.
Dave Arneson's Wikipedia Entry
Gary Gygax himself passed away last year due to heart failure.
Like Gary Gygax, I'm glad I got the opportunity to meet with Dave Arneson a couple of years back at GenCon and thank him for the work he did that inspired such a fascinating and creative social dynamic.